The Carcinogenic Potency Project
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About [Edit]
The Carcinogenic Potency Database (CPDB) is a unique and widely used international resource of results from 6153 chronic, long-term animal cancer tests on 1485 chemicals. CPDB provides a standardized and easily accessible database with qualitative and quantitative analyses of both positive and negative experiments that have been published in the general literature through 1997 and by the National Cancer Institute/National Toxicology Program through 1998.
For each experiment, information is included on species, strain, and sex of test animal; features of experimental protocol such as route of administration, duration of dosing, dose level(s) in mg/kg body weight/day, and duration of experiment; target organ, tumor type, and tumor incidence; carcinogenic potency (TD50) and its statistical significance; shape of the dose-response, author's opinion as to carcinogenicity, and literature citation.
This Web site is designed to facilitate use of the CPDB by presenting the information in summary tables as well as in the detailed plots that have been published. The boxes above link to the data in several formats suitable for either (1) screen viewing, or (2) printing, or (3) reading the data into statistical packages and spreadsheets. The Web site is fully searchable by all fields and provides documentation on inclusion rules, methods used to develop the CPDB, guides to the various formats, and full text of our publications. For chemicals in the CPDB, structure, SMILES, InChI codes are reported.
For each experiment, information is included on species, strain, and sex of test animal; features of experimental protocol such as route of administration, duration of dosing, dose level(s) in mg/kg body weight/day, and duration of experiment; target organ, tumor type, and tumor incidence; carcinogenic potency (TD50) and its statistical significance; shape of the dose-response, author's opinion as to carcinogenicity, and literature citation.
This Web site is designed to facilitate use of the CPDB by presenting the information in summary tables as well as in the detailed plots that have been published. The boxes above link to the data in several formats suitable for either (1) screen viewing, or (2) printing, or (3) reading the data into statistical packages and spreadsheets. The Web site is fully searchable by all fields and provides documentation on inclusion rules, methods used to develop the CPDB, guides to the various formats, and full text of our publications. For chemicals in the CPDB, structure, SMILES, InChI codes are reported.


